Novel Loop-Mediated Isothermal Amplification Method for Detection of the JP2 Clone of Aggregatibacter actinomycetemcomitans in Subgingival Plaque | Zendy

Mitsuko Seki | Zendy; Knud Poulsen | Zendy; Dorte Haubek | Zendy; Mogens Kilian | Zendy

Open Access

Novel Loop-Mediated Isothermal Amplification Method for Detection of the JP2 Clone of Aggregatibacter actinomycetemcomitans in Subgingival Plaque

Author(s) -

Mitsuko Seki,

Knud Poulsen,

Dorte Haubek,

Mogens Kilian

Publication year - 2007

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.02107-07

Subject(s) - aggregatibacter actinomycetemcomitans , loop mediated isothermal amplification , periodontitis , clone (java method) , population , microbiology and biotechnology , biology , aggressive periodontitis , medicine , dentistry , porphyromonas gingivalis , gene , genetics , dna , environmental health

We developed a loop-mediated isothermal amplification method that detects the JP2 clone of Aggregatibacter actinomycetemcomitans, which induces aggressive periodontitis in adolescents of North and West African descents. Being independent of special equipment, this specific and sensitive method offers significant advantages for screening of patients on a population basis and in clinical settings.

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