Fatal Epstein-Barr Virus Primo Infection in a 25-Year-Old Man Treated with Azathioprine for Crohn's Disease | Zendy

Yohan N’Guyen | Zendy; Laurent Andréoletti | Zendy; Martine Patey | Zendy; Carinne LecoqLafon | Zendy; Pascale Cornillet | Zendy; A. Léon | Zendy; R. Jaussaud | Zendy; Claire Fieschi | Zendy; C. Strady | Zendy

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Fatal Epstein-Barr Virus Primo Infection in a 25-Year-Old Man Treated with Azathioprine for Crohn's Disease

Author(s) -

Yohan N’Guyen,

Laurent Andréoletti,

Martine Patey,

Carinne LecoqLafon,

Pascale Cornillet,

A. Léon,

R. Jaussaud,

Claire Fieschi,

C. Strady

Publication year - 2009

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.02052-08

Subject(s) - azathioprine , mononucleosis , crohn's disease , inflammatory bowel disease , medicine , virus , disease , epstein–barr virus , immunology , hemophagocytic lymphohistiocytosis , epstein–barr virus infection , virology , pathology

We report a case of Epstein-Barr virus (EBV) primo infection with the development of successive infectious mononucleosis, hemophagocytic lymphohistiocytosis, and B-cell lymphoproliferative disorder in a patient treated with azathioprine for Crohn's disease. This case report suggests that specific EBV-related clinical and virological management should be considered when treating a patient with inflammatory bowel disease with azathioprine.

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