Identification of Beijing Lineage Mycobacterium tuberculosis with Combined Mycobacterial Interspersed Repetitive Unit Loci 26, 31, and ETR-A | Zendy

Pei-Ju Chin | Zendy; Chen-Che Chiu | Zendy; Ruwen Jou | Zendy

Open Access

Identification of Beijing Lineage Mycobacterium tuberculosis with Combined Mycobacterial Interspersed Repetitive Unit Loci 26, 31, and ETR-A

Author(s) -

Pei-Ju Chin,

Chen-Che Chiu,

Ruwen Jou

Publication year - 2007

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.02036-06

Subject(s) - genotyping , mycobacterium tuberculosis , lineage (genetic) , tuberculosis , biology , beijing , identification (biology) , virology , genotype , genetics , gene , medicine , pathology , geography , botany , archaeology , china

A rapid method for identification of Beijing lineage Mycobacterium tuberculosis is still needed in regions of tuberculosis endemicity, especially if genotyping methods are not readily accessible. After analyzing 1,557 clinical isolates, a PCR method with combined mycobacterial interspersed repetitive unit loci 26, 31, and ETR-A for differentiation of Beijing lineage isolates was established, the sensitivity and specificity of which are 94.7% and 98.5%, respectively.

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