Clinical Characteristics, Laboratory Identification, and In Vitro Antifungal Susceptibility of Yarrowia (Candida) lipolytica Isolates Causing Fungemia: a Multicenter, Prospective Surveillance Study | Zendy

Ying Zhao | Zendy; Jasper FukWoo Chan | Zendy; ChiChing Tsang | Zendy; He Wang | Zendy; Da-Wen Guo | Zendy; Yuhong Pan | Zendy; Yuling Xiao | Zendy; Na Yue | Zendy; Jonathan Hon-Kwan Chen | Zendy; Susanna K. P. Lau | Zendy; Yingchun Xu | Zendy; Patrick C. Y. Woo | Zendy

Open Access

Clinical Characteristics, Laboratory Identification, and In Vitro Antifungal Susceptibility of Yarrowia (Candida) lipolytica Isolates Causing Fungemia: a Multicenter, Prospective Surveillance Study

Author(s) -

Ying Zhao,

Jasper FukWoo Chan,

ChiChing Tsang,

He Wang,

Da-Wen Guo,

Yuhong Pan,

Yuling Xiao,

Na Yue,

Jonathan Hon-Kwan Chen,

Susanna K. P. Lau,

Yingchun Xu,

Patrick C. Y. Woo

Publication year - 2015

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.01985-15

Subject(s) - yarrowia , fungemia , microbiology and biotechnology , voriconazole , biology , amphotericin b , internal transcribed spacer , candida tropicalis , echinocandins , ribosomal rna , candida albicans , antifungal , caspofungin , gene , genetics

Our case series showed that uncomplicated Yarrowia lipolytica fungemia might be treated with catheter removal alone. The Vitek 2 YST identification (ID) card system, matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS), and internal transcribed spacer and 25S nuclear ribosomal DNA (nrDNA) gene sequencing provided reliable identification. All isolates had low MICs to voriconazole, echinocandins, and amphotericin B.

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