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The iC-GPC assay (iCubate, Huntsville, AL) provides a molecular option for the rapid, on-demand analysis of positive blood cultures. A preliminary evaluation of the iC-GPC assay using 203 clinical or seeded specimens demonstrated a sensitivity of 93.8% to 100% and a specificity of 98.0% to 100% for the identification of five Gram-positive bacterial species (Staphylococcus aureus ,Staphylococcus epidermidis ,Streptococcus pneumoniae ,Enterococcus faecalis , andEnterococcus faecium ) and three associated genetic resistance determinants (mecA ,vanA , andvanB ) in positive blood culture broths.

journal of clinical microbiology

Preliminary Evaluation of the Research-Use-Only (RUO) iCubate iC-GPC Assay for Identification of Select Gram-Positive Bacteria and Their Resistance Determinants in Blood Culture Broths