Characterization of Genetic Diversity of Carbapenem-Resistant Acinetobacter baumannii Clinical Strains Collected from 2004 to 2007 | Zendy

Chao Qi | Zendy; Michael Malczynski | Zendy; Michelle Parker | Zendy; Marc H. Scheetz | Zendy

Open Access

Characterization of Genetic Diversity of Carbapenem-Resistant Acinetobacter baumannii Clinical Strains Collected from 2004 to 2007

Author(s) -

Chao Qi,

Michael Malczynski,

Michelle Parker,

Marc H. Scheetz

Publication year - 2008

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.01877-07

Subject(s) - meropenem , acinetobacter baumannii , imipenem , microbiology and biotechnology , genotype , carbapenem , biology , acinetobacter , pulsed field gel electrophoresis , antibiotic resistance , antibiotics , gene , bacteria , genetics , pseudomonas aeruginosa

Genotypes of carbapenem-resistant Acinetobacter baumannii collected by the clinical microbiology laboratory of a university hospital in Chicago, IL, between 2004 and 2007 were analyzed by pulsed-field gel electrophoresis. A single genotype established predominance after being introduced in 2005. Analysis of carbapenemases by PCR revealed that imipenem resistance but not meropenem resistance was associated with the presence of bla(OXA-23) and bla(OXA-40) genes.

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