Detection of SHV-Type Extended-Spectrum Beta-Lactamase in Enterobacter Isolates | Zendy

Trent G. Towne | Zendy; James S. Lewis | Zendy; Mónica Herrera | Zendy; Brian L. Wickes | Zendy; James H. Jorgensen | Zendy

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Detection of SHV-Type Extended-Spectrum Beta-Lactamase in Enterobacter Isolates

Author(s) -

Trent G. Towne,

James S. Lewis,

Mónica Herrera,

Brian L. Wickes,

James H. Jorgensen

Publication year - 2009

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.01875-09

Subject(s) - cefepime , enterobacter , beta lactam , beta lactamase , microbiology and biotechnology , biology , antibiotics , imipenem , escherichia coli , antibiotic resistance , genetics , gene

One hundred four Enterobacter isolates were tested by standard CLSI disk diffusion methods for detecting extended-spectrum beta-lactamases (ESBLs) and with cefepime-clavulanate disk combinations. SHV-12 was produced by 8.7% of isolates. The cefepime-clavulanate combination provided 88% sensitivity and 91% specificity for the detection of SHV-12 ESBL.

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