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Bacteremia and Infective Endocarditis Caused by a Non-Daptomycin-Susceptible, Vancomycin-Intermediate, and Methicillin-Resistant Staphylococcus aureus Strain in Taiwan
Author(s) -
YuTsung Huang,
ChihTing Lin,
ChunHsing Liao,
ChungWei Lee,
PoRen Hsueh
Publication year - 2008
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.01844-07
Subject(s) - daptomycin , bacteremia , linezolid , vancomycin , staphylococcus aureus , medicine , infective endocarditis , endocarditis , microbiology and biotechnology , staphylococcal infections , fusidic acid , methicillin resistant staphylococcus aureus , glycopeptide antibiotic , glycopeptide , antibiotics , surgery , biology , bacteria , genetics
We describe the development of nonsusceptibility to daptomycin and vancomycin during treatment for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia associated with infective endocarditis and probable septic thrombophlebitis in a uremic patient. MRSA bacteremia persisted during glycopeptide and subsequent daptomycin treatment but cleared after 5 days' treatment with linezolid and fusidic acid.

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