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Recurrent Methicillin-Resistant Staphylococcus aureus Cutaneous Abscesses and Selection of Reduced Chlorhexidine Susceptibility during Chlorhexidine Use
Author(s) -
Ryan C. Johnson,
Carey D. Schlett,
Katrina B. Crawford,
Jeffrey B. Lanier,
D. Scott Merrell,
Michael W. Ellis
Publication year - 2015
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.01771-15
Subject(s) - chlorhexidine , staphylococcus aureus , methicillin resistant staphylococcus aureus , microbiology and biotechnology , efflux , medicine , abscess , staphylococcal infections , micrococcaceae , antibiotics , antibacterial agent , biology , bacteria , surgery , dentistry , genetics
We describe the selection of reduced chlorhexidine susceptibility during chlorhexidine use in a patient with two episodes of cutaneous USA300 methicillin-resistantStaphylococcus aureus abscess. The second clinical isolate harbors a novel plasmid that encodes the QacA efflux pump. Greater use of chlorhexidine for disease prevention warrants surveillance for resistance.

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