New Immunoenzymatic Strategy for Rapid and Selective Growth of Salmonella | Zendy

Isabelle Ponsard | Zendy; Patrice Soumillion | Zendy

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New Immunoenzymatic Strategy for Rapid and Selective Growth of Salmonella

Author(s) -

Isabelle Ponsard,

Patrice Soumillion

Publication year - 2012

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.01765-12

Subject(s) - salmonella , bacteria , microbiology and biotechnology , monoclonal antibody , conjugate , biology , enterobacteriaceae , penicillin , antigen , antibiotics , antibiotic resistance , antibody , escherichia coli , immunology , genetics , gene , mathematical analysis , mathematics

We demonstrated that an exogenous conjugate consisting of a β-lactamase and a monoclonal antibody against a surface antigen of Salmonella is capable of conferring selective penicillin resistance on bacteria. This immunoenzymatic approach allows the rapid growth and detection of specific bacteria and may find other applications when temporary and nongenetic antibiotic resistance is required.

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