Rapid Time to Results and High Sensitivity of the CarbaNP Test on Early Cultures | Zendy

Laiyang Lee | Zendy; Tony M. Korman | Zendy; Maryza Graham | Zendy

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Rapid Time to Results and High Sensitivity of the CarbaNP Test on Early Cultures

Author(s) -

Laiyang Lee,

Tony M. Korman,

Maryza Graham

Publication year - 2014

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.01682-14

Subject(s) - test (biology) , sensitivity (control systems) , medicine , biology , engineering , ecology , electronic engineering

For rapid results, we adapted the CarbaNP test by using 5-hour-old cultures; the sensitivity and specificity for detection of carbapenemase production were 100% for non-OXA-producing organisms. The sensitivity from early cultures was 94% for detection of carbapenemase production in Enterobacteriaceae strains. Utilizing younger cultures allows the test to be incorporated into a single day's workflow, facilitating timely patient care and antimicrobial stewardship.

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