Open AccessReversion of Influenza A (H3N2) Virus from Amantadine Resistant to Amantadine Sensitive by Further Reassortment in Japan during the 2006-to-2007 Influenza Season
Author(s) -
Yuki Furuse,
Akira Suzuki,
Taro Kamigaki,
Midori Shimizu,
Naoko Fuji,
Hitoshi Oshitani
Publication year - 2009
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.01622-08
Subject(s) - reassortment , amantadine , virology , biology , reversion , virus , influenza a virus , microbiology and biotechnology , genetics , gene , covid-19 , medicine , infectious disease (medical specialty) , disease , pathology , phenotype
In the 2006-to-2007 influenza season, amantadine-sensitive strains were found among the N-lineage influenza A (H3N2) viruses, which were previously believed to be associated with amantadine resistance. Whole-genome sequencing results indicated that this was due to a further reassortment event.