Whole-Genome Sequencing for Characterization of Capsule Locus and Prediction of Serogroup of Invasive Meningococcal Isolates
Author(s) -
Henju Marjuki,
Nadav Topaz,
Lorraine D. RodriguezRivera,
Edward Ramos,
Caelin Cubeñas-Potts,
Alexander Chen,
Adam C. Retchless,
Gregory Doho,
Xin Wang
Publication year - 2018
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.01609-18
Subject(s) - neisseria meningitidis , neisseriaceae , meningococcal disease , locus (genetics) , microbiology and biotechnology , serotype , biology , virology , polymerase chain reaction , genome , neisseria , multilocus sequence typing , whole genome sequencing , meningococcal infections , genetics , gene , bacteria , genotype , antibiotics
Invasive meningococcal disease is mainly caused byNeisseria meningitidis serogroups A, B, C, X, W, and Y. The serogroup is typically determined by slide agglutination serogrouping (SASG) and real-time PCR (RT-PCR).
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