Open AccessClinical Significance of Low-Positive Histoplasma Urine Antigen Results
Author(s) -
Elitza S. Theel,
Poornima Ramanan
Publication year - 2014
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.01598-14
Subject(s) - histoplasmosis , histoplasma , urine , antigen , clinical significance , medicine , histoplasma capsulatum , biomarker , immunology , pathology , biology , biochemistry
Histoplasma urine antigen (UAg) detection is an important biomarker for histoplasmosis. The clinical significance of low-positive (<0.6 ng/ml) UAg results was evaluated in 25 patients without evidence of prior Histoplasma infection. UAg results from 12/25 (48%) patients were considered falsely positive, suggesting that low-positive UAg values should be interpreted cautiously.
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