HIV-Selectest Enzyme Immunoassay and Rapid Test: Ability To Detect Seroconversion following HIV-1 Infection
Author(s) -
Surender Khurana,
Philip J. Norris,
Michael P. Busch,
Barton F. Haynes,
Susan Park,
Pretty Sasono,
Koleka Mlisana,
Salim S. Abdool Karim,
Frederick Hecht,
Joseph Mulenga,
Elwyn Chomba,
Eric Hunter,
Susan Allen,
George J. Nemo,
Isaac R. RodriguezChavez,
Joseph B. Margolick,
Hana Golding
Publication year - 2009
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.01573-09
Subject(s) - immunoassay , seroconversion , gp41 , human immunodeficiency virus (hiv) , virology , antibody , medicine , immunology , viral disease , immunopathology , epitope
HIV-Selectest is a serodiagnostic enzyme immunoassay (EIA), containing p6 and gp41 peptides, designed to differentiate between vaccine-induced antibodies and true infections. A rapid test version of the HIV-Selectest was developed. Both assays detected HIV antibodies in men and women within 2 to 4 weeks of infection, with sensitivity similar to third-generation EIAs.
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