Open AccessMonitoring of Stool Microbiota in Subjects with Diarrhea Indicates Distortions in Composition
Author(s) -
Volker Mai,
Christopher R. Braden,
Jill Heckendorf,
B A Baiba Pironis,
Jon Mark Hirshon
Publication year - 2006
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.01542-06
Subject(s) - diarrhea , temperature gradient gel electrophoresis , asymptomatic , feces , biology , microbiology and biotechnology , bacteria , gastroenterology , medicine , genetics , 16s ribosomal rna
We utilized denaturing gradient gel electrophoresis profiling to survey stool microbiota in 175 persons with diarrhea and 113 asymptomatic persons in a diarrhea surveillance study. Compared with healthy controls, the microbiota profiles in diarrhea cases more frequently exhibited decreased diversity and strong bands indicating the overgrowth of selected bacteria or bacterial groups.