Multiple Broad-Spectrum Beta-Lactamase Targets for Comprehensive Surveillance
Author(s) -
Kathy A. Mangold,
Barbara L. Voss,
Kamaljit Singh,
Richard B. Thomson,
Donna Schora,
Lance R. Peterson,
Karen L. Kaul
Publication year - 2013
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.01488-13
Subject(s) - beta (programming language) , broad spectrum , beta lactamase , microbiology and biotechnology , virology , medicine , computational biology , biology , computer science , chemistry , genetics , escherichia coli , combinatorial chemistry , gene , programming language
Real-time PCR testing for blaKPC, blaNDM, blaVIM, blaIMP, and blaCTX-M was performed on rectal swabs obtained from residents of two long-term acute-care facilities. While blaKPC was detected in 69/102 swabs (67.6%), testing for four other targets increased the positivity rate for a broad-spectrum β-lactamase to 73.5% (McNemar's P = 0.03).
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom