Combination of Nonstructural Protein 1-Based Enzyme-Linked Immunosorbent Assays Can Detect and Distinguish Various Dengue Virus and Zika Virus Infections
Author(s) -
Jasmine Tyson,
Wen-Yang Tsai,
JihJin Tsai,
Carlos Brites,
Ludvig Mässgård,
HanHa Chai,
Célia Pedroso,
Jan Felix Drexler,
Susan L. Stramer,
Ángel Balmaseda,
Eva Harris,
WeiKung Wang
Publication year - 2018
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.01464-18
Subject(s) - zika virus , dengue virus , virology , dengue fever , serotype , virus , biology , outbreak , flavivirus
The recent outbreaks of Zika virus (ZIKV) and associated birth defects in regions of dengue virus (DENV) endemicity emphasize the need for sensitive and specific serodiagnostic tests. We reported previously that enzyme-linked immunosorbent assays (ELISAs) based on the nonstructural protein 1 (NS1) of DENV serotype 1 (DENV1) and ZIKV can distinguish primary DENV1, secondary DENV, and ZIKV infections.
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