Mycobacterium tuberculosis Complex and Mycobacterial Heat Shock Proteins in Lymph Node Tissue from Patients with Pulmonary Sarcoidosis | Zendy

Anna Dubaniewicz | Zendy; Mirosława Dubaniewicz-Wybieralska | Zendy; Adam Sternau | Zendy; Zofia Zwolska | Zendy; Ewa IżyckaŚwieszewska | Zendy; Ewa AugustynowiczKopeć | Zendy; Jarosław Skokowski | Zendy; Mahavir Singh | Zendy; L Zimnoch | Zendy

Open Access

Mycobacterium tuberculosis Complex and Mycobacterial Heat Shock Proteins in Lymph Node Tissue from Patients with Pulmonary Sarcoidosis

Author(s) -

Anna Dubaniewicz,

Mirosława Dubaniewicz-Wybieralska,

Adam Sternau,

Zofia Zwolska,

Ewa IżyckaŚwieszewska,

Ewa AugustynowiczKopeć,

Jarosław Skokowski,

Mahavir Singh,

L Zimnoch

Publication year - 2006

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.01433-06

Subject(s) - sarcoidosis , mycobacterium tuberculosis , tuberculosis , medicine , lymph node , heat shock protein , pulmonary disease , pathology , pulmonary tuberculosis , mycobacterium , shock (circulatory) , immunology , lymph , microbiology and biotechnology , biology , genetics , gene

We demonstrated that not whole Mycobacterium tuberculosis but its particular antigens, hsp70(Mtb), hsp65(Mtb), and hsp16(Mtb), are present in lymph node tissues of patients with sarcoidosis (SA). hsp16(Mtb) occurs in the early stage of SA, whereas hsp70(Mtb) occurs in stage II of SA. hsp65(Mtb) is highly expressed in the capillary vessels in lymph node tissues in patients with SA.

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