Commentary: Next-Generation Sequencing: a Diagnostic One-Stop Shop for Hepatitis C? | Zendy

Mario Poljak | Zendy

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Commentary: Next-Generation Sequencing: a Diagnostic One-Stop Shop for Hepatitis C?

Author(s) -

Mario Poljak

Publication year - 2016

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.01423-16

Subject(s) - virology , genotype , dna sequencing , hepatitis c virus , hepatitis c , clinical microbiology , whole genome sequencing , drug resistance , genome , biology , virus , computational biology , genetics , microbiology and biotechnology , gene

Before starting chronic hepatitis C treatment, the viral genotype/subtype has to be accurately determined and potentially coupled with drug resistance testing. Due to the high genetic variability of the hepatitis C virus, this can be a demanding task that can potentially be streamlined by viral whole-genome sequencing using next-generation sequencing as demonstrated by an article in this issue of the Journal of Clinical Microbiology by E. Thomson, C. L. C. Ip, A. Badhan, M. T. Christiansen, W. Adamson, et al. (J Clin Microbiol. 54:2455-2469, 2016, http://dx.doi.org/10.1128/JCM.00330-16).

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