Open AccessPredominance and Circulation of Enteric Viruses in the Region of Greater Cairo, Egypt
Author(s) -
A.H. Kamel,
Mohammed Farid Ali,
Hala G. Elnady,
Alexis de Rougemont,
Pierre Pothier,
Gaël Belliot
Publication year - 2009
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.01381-08
Subject(s) - rotavirus , norovirus , astrovirus , virology , biology , feces , population , typing , reoviridae , phylogenetic tree , virus , capsid , molecular epidemiology , enteric virus , microbiology and biotechnology , genotype , gene , genetics , medicine , environmental health
The circulation of enteric viruses among the population of Cairo, Egypt, between March 2006 and February 2007 was studied. At least one virus was detected in 50% of fecal samples, 57.4% of which were positive for rotavirus, 26% for norovirus, 10.4% for adenovirus, and 1.7% for astrovirus. Over 10% of infections were mixed infections. Rotavirus typing showed that G1P[8] and G2P[4] were predominant but that the unusual G12P[4] and G12P[6] reassortants were also present. Among the noroviruses, half belonged to the predominant GGII.4 cluster. The phylogenetic analysis of the capsid gene suggested that GGII.4 strains from Cairo were similar to those circulating elsewhere. It also showed the emergence of new GGII.4 variants that were not associated with any previously known GGII.4 isolate. Further studies are required to assess the disease burden of enteric viruses in Egypt and the impact of atypical strains.