Genotyping of 353 Staphylococcus aureus Bloodstream Isolates Collected between 2004 and 2009 at a Norwegian University Hospital and Potential Associations with Clinical Parameters | Zendy

Hege Vangstein Aamot | Zendy; Anita Blomfeldt | Zendy; Arne Nørgaard Eskesen | Zendy

Open Access

Genotyping of 353 Staphylococcus aureus Bloodstream Isolates Collected between 2004 and 2009 at a Norwegian University Hospital and Potential Associations with Clinical Parameters

Author(s) -

Hege Vangstein Aamot,

Anita Blomfeldt,

Arne Nørgaard Eskesen

Publication year - 2012

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.01352-12

Subject(s) - staphylococcus aureus , genotyping , genotype , microbiology and biotechnology , leukocidin , norwegian , biology , toxic shock syndrome , staphylococcal infections , methicillin resistant staphylococcus aureus , gene , genetics , bacteria , linguistics , philosophy

We analyzed 353Staphylococcus aureus bloodstream isolates from 2004 to 2009 to identify dominant genotypes, changes over time, and associations between genotype, phenotype, and clinical parameters. The isolates were genotyped with regard tospa type and presence of Panton-Valentine leukocidin and toxic shock syndrome toxin 1-encoding genes. A high level of genetic diversity was detected. All but three isolates were methicillin sensitive. Interestingly,spa clonal complex 021 showed a weak association with higher all-cause hospital mortality.

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