Clinical Potential of C-Reactive Protein and Procalcitonin Serum Concentrations To Guide Differential Diagnosis and Clinical Management of Pneumococcal and Legionella Pneumonia | Zendy

Rosa BellmannWeiler | Zendy; Mathias Ausserwinkler | Zendy; Katharina Kurz | Zendy; Igor Theurl | Zendy; Günter Weiß | Zendy

Open Access

Clinical Potential of C-Reactive Protein and Procalcitonin Serum Concentrations To Guide Differential Diagnosis and Clinical Management of Pneumococcal and Legionella Pneumonia

Author(s) -

Rosa BellmannWeiler,

Mathias Ausserwinkler,

Katharina Kurz,

Igor Theurl,

Günter Weiß

Publication year - 2010

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.01348-09

Subject(s) - procalcitonin , pneumonia , legionella pneumophila , streptococcus pneumoniae , medicine , c reactive protein , gastroenterology , community acquired pneumonia , differential diagnosis , immunology , microbiology and biotechnology , sepsis , pathology , biology , bacteria , inflammation , antibiotics , genetics

We retrospectively analyzed the records of 61 hospitalized patients with community-acquired pneumonia (CAP) caused byS treptococcus pneumoniae orL egionella pneumophila . We found that serum procalcitonin and sodium concentrations were significantly lower, and ferritin levels were significantly higher, in patients infected withL. pneumophila than in those infected withS. pneumoniae . The ratio of C-reactive protein to procalcitonin significantly distinguished between the groups. High procalcitonin levels were associated with an adverse clinical course.

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