Open AccessBuruli Ulcer Disease in Travelers and Differentiation of Mycobacterium ulcerans Strains from Northern Australia
Author(s) -
Caroline J. Lavender,
Maria Globan,
Paul D. R. Johnson,
Patrick G. P. Charles,
G. Jenkin,
Niladri Ghosh,
Benjamin Clark,
Marianne Martinello,
Janet Fyfe
Publication year - 2012
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.01324-12
Subject(s) - mycobacterium ulcerans , buruli ulcer , biology , typing , epidemiology , tropical disease , skin ulcer , virology , genotype , molecular epidemiology , microbiology and biotechnology , disease , medicine , dermatology , genetics , pathology , gene
Buruli ulcer (BU) is a necrotizing infection of skin and soft tissue caused by Mycobacterium ulcerans. In Australia, most cases of BU are linked to temperate, coastal Victoria and tropical, northern Queensland, and strains from these regions are distinguishable by variable-number tandem repeat (VNTR) typing. We present an epidemiological investigation of five patients found to have been infected during interstate travel and describe two nucleotide polymorphisms that differentiate M. ulcerans strains from northern Australia.
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