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A Cost-Effective Method for Identifying Enterobacterales with OXA-181
Author(s) -
Gisele Peirano,
Yasufumi Matsumura,
Diego B. Nóbrega,
Johann Pitout
Publication year - 2019
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.01281-19
Subject(s) - loop mediated isothermal amplification , bacteria , confidence interval , biology , enterobacteriaceae , indian subcontinent , microbiology and biotechnology , enzyme , computational biology , medicine , genetics , escherichia coli , gene , biochemistry , history , dna , ancient history
OXA-181 is the second most common global OXA-48-like carbapenemase and is endemic in the Indian subcontinent. Molecular studies have shown thatEnterobacterales with OXA-181 are often introduced into regions of nonendemicity. Distinguishing OXA-181 from other OXA-48-like enzymes often requires sequencing, which is rather expensive and time-consuming.

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