Open AccessMulticenter Evaluation of Colistin Broth Disk Elution and Colistin Agar Test: a Report from the Clinical and Laboratory Standards Institute
Author(s) -
Romney M. Humphries,
Daniel A. Green,
Audrey N. Schuetz,
Yehudit Bergman,
Shawna Lewis,
Rebecca Yee,
Stephania Stump,
Mabel Lopez,
Nenad Macesic,
AnneCatrin Uhlemann,
Peggy C. Kohner,
Nicolynn C. Cole,
Patricia J. Simner
Publication year - 2019
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.01269-19
Subject(s) - colistin , polymyxin , clinical microbiology , agar , polymyxin b , microbiology and biotechnology , antimicrobial , medicine , chromatography , biology , chemistry , antibiotics , bacteria , genetics
Susceptibility testing of the polymyxins (colistin and polymyxin B) is challenging for clinical laboratories. The Clinical and Laboratory Standards Institute (CLSI) Antimicrobial Susceptibility Testing Subcommittee evaluated two methods to enable accurate testing of these agents. These methods were a colistin broth disk elution (CBDE) and a colistin agar test (CAT), the latter of which was evaluated using two inoculum volumes, 1 μl (CAT-1) and 10 μl (CAT-10).
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