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Prospective Evaluation of Molecular Assays for Diagnosis of Vaginitis
Author(s) -
Sandra S. Richter,
Joshua Otiso,
Oluwatosin Goje,
Sherilynn Vogel,
Jory Aebly,
George Keller,
Hillary Van Heule,
Danielle Wehn,
Amy L. Stephens,
Salena Zanotti,
Tricia Johnson,
Sixto M. Leal,
Gary W. Procop
Publication year - 2019
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.01264-19
Subject(s) - bacterial vaginosis , vaginitis , gardnerella vaginalis , medicine , microbiology and biotechnology , lactobacillus , biology , immunology , gynecology , bacteria , genetics
Molecular tests to diagnose conditions involving the disruption of normal microbiota are difficult to optimize. Using Nugent-scored Gram stain (NS) as the reference standard, we evaluated the performance of 3 molecular assays for the diagnosis of bacterial vaginosis (BV) and examined the impact of an incremental increase in bacterial targets.

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