Evaluation of Commercial Rubella Immunoglobulin G Avidity Assays | Zendy

Samira Mubareka | Zendy; Hannah Richards | Zendy; Michael J. Gray | Zendy; Graham Tipples | Zendy

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Evaluation of Commercial Rubella Immunoglobulin G Avidity Assays

Author(s) -

Samira Mubareka,

Hannah Richards,

Michael J. Gray,

Graham Tipples

Publication year - 2006

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.01243-06

Subject(s) - avidity , kappa , rubella , rubella virus , immunoglobulin g , virology , antibody , medicine , immunology , biology , vaccination , measles , linguistics , philosophy

We compared the performances of five commercial rubella virus immunoglobulin G (IgG) avidity assays. The Adaltis (kappa = 0.28) and Diesse (kappa = 0.33) assays showed poor correlation, the Behring assay (kappa = 0.68) showed good correlation, and the Euroimmun (kappa = 0.95) and Radim (kappa = 0.94) assays showed excellent correlation with a well-established in-house rubella virus IgG avidity assay. The Euroimmun and Radim assays were statistically significantly better than the other commercial assays (P < 0.01).

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