Predicted Configurations of Oligosaccharide Extensions in the Lipooligosaccharide of Nontypeable Haemophilus influenzae Isolates
Author(s) -
Kirk W. McCrea,
Jingping Xie,
Deborah Danıel,
Justin Theophilus Ulrich-Lewis,
Lixin Zhang
Publication year - 2014
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.01113-14
Subject(s) - haemophilus influenzae , oligosaccharide , microbiology and biotechnology , haemophilus , pasteurellaceae , throat , biology , bacteria , genetics , antibiotics , anatomy , biochemistry
Lipooligosaccharide configurations were predicted in nontypeableHaemophilus influenzae isolates based on the presence of seven oligosaccharide extension-initiating genes (or alleles). Predicted configurations with 2 to 3 oligosaccharide extensions were more prevalent among middle ear than throat strains. In addition, strains with these configurations averaged higher levels of serum resistance than strains with other configurations.
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