Comparison of the Human Immunodeficiency Virus (HIV) Type 1-Specific Immunoglobulin G Capture Enzyme-Linked Immunosorbent Assay and the Avidity Index Method for Identification of Recent HIV Infections | Zendy

Stephan Loschen | Zendy; Jörg Bätzing-Feigenbaum | Zendy; Gabriele Poggensee | Zendy; Christiane Cordes | Zendy; B Hintsche | Zendy; Michael Rausch | Zendy; S Dupke | Zendy; Silvia Gohlke-Micknis | Zendy; Jana Rödig | Zendy; Osamah Hamouda | Zendy; Claudia Kücherer | Zendy

Open Access

Comparison of the Human Immunodeficiency Virus (HIV) Type 1-Specific Immunoglobulin G Capture Enzyme-Linked Immunosorbent Assay and the Avidity Index Method for Identification of Recent HIV Infections

Author(s) -

Stephan Loschen,

Jörg Bätzing-Feigenbaum,

Gabriele Poggensee,

Christiane Cordes,

B Hintsche,

Michael Rausch,

S Dupke,

Silvia Gohlke-Micknis,

Jana Rödig,

Osamah Hamouda,

Claudia Kücherer

Publication year - 2007

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.01055-07

Subject(s) - avidity , virology , antibody , immunoglobulin g , virus , human immunodeficiency virus (hiv) , viral disease , immunology , immunopathology , biology , medicine

The sensitivity and specificity of the human immunodeficiency virus (HIV) type 1-specific immunoglobulin G capture enzyme-linked immunosorbent assay (BED-CEIA) were compared with those of the avidity index method to identify recent HIV infection using a panel of 148 samples (81 patients) representing durations of infection ranging from 0 to 222 weeks. The results from the two tests were similar (sensitivity of 80% versus 74% [P = 0.53]; specificity of 86% versus 82% [P = 0.67]).

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