Open AccessComparison of the Human Immunodeficiency Virus (HIV) Type 1-Specific Immunoglobulin G Capture Enzyme-Linked Immunosorbent Assay and the Avidity Index Method for Identification of Recent HIV Infections
Author(s) -
Stephan Loschen,
Jörg Bätzing-Feigenbaum,
Gabriele Poggensee,
Christiane Cordes,
B. Hintsche,
Michael Rausch,
S Dupke,
Silvia Gohlke-Micknis,
Jana Rödig,
Osamah Hamouda,
Claudia Kücherer
Publication year - 2008
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.01055-07
Subject(s) - avidity , virology , antibody , immunoglobulin g , virus , human immunodeficiency virus (hiv) , viral disease , immunology , immunopathology , biology , medicine
The sensitivity and specificity of the human immunodeficiency virus (HIV) type 1-specific immunoglobulin G capture enzyme-linked immunosorbent assay (BED-CEIA) were compared with those of the avidity index method to identify recent HIV infection using a panel of 148 samples (81 patients) representing durations of infection ranging from 0 to 222 weeks. The results from the two tests were similar (sensitivity of 80% versus 74% [P = 0.53]; specificity of 86% versus 82% [P = 0.67]).