Performance of the Aptima HIV-1 RNA Qualitative Assay with 16- and 32-Member Specimen Pools | Zendy

Steven F. Ethridge | Zendy; Clyde E. Hart | Zendy; Debra L. Hanson | Zendy; Monica M. Parker | Zendy; Timothy J. Sullivan | Zendy; Berry Bennett | Zendy; Petrice Stephens | Zendy; Joslyn Hilliard | Zendy; Pragna Patel | Zendy

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Performance of the Aptima HIV-1 RNA Qualitative Assay with 16- and 32-Member Specimen Pools

Author(s) -

Steven F. Ethridge,

Clyde E. Hart,

Debra L. Hanson,

Monica M. Parker,

Timothy J. Sullivan,

Berry Bennett,

Petrice Stephens,

Joslyn Hilliard,

Pragna Patel

Publication year - 2010

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.01030-10

Subject(s) - rna , virology , human immunodeficiency virus (hiv) , biology , lentivirus , genetics , viral disease , gene

The Aptima HIV-1 RNA qualitative assay tested with a WHO-approved HIV type 1 RNA standard in 16- and 32-member pools detected 100% of the pools (1,070 and 2,130 HIV-1 RNA copies/ml/pool, respectively), thus exceeding the FDA-required lower limit of detection. The Aptima test can be used to screen for acute-phase HIV infection.

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