Open AccessCharacterization of RD-114 Virus Isolated from a Commercial Canine Vaccine Manufactured Using CRFK Cells
Author(s) -
Rokusuke Yoshikawa,
Eiji Sato,
Tatsuhiko Igarashi,
Takayuki Miyazawa
Publication year - 2010
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00992-10
Subject(s) - virology , virus , retrovirus , biology , endogenous retrovirus , gene , genome , genetics
Recently, we found that several commercial pet vaccines were contaminated with an infectious endogenous retrovirus, RD-114-related virus. Here, we determined the entire nucleotide sequences of RD-114-related viruses isolated from CRFK cells and a vaccine manufactured using CRFK cells. These RD-114-related viruses were nearly identical to the authentic RD-114 virus.
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