Real-Time PCR as a Prognostic Tool for Human Congenital Toxoplasmosis | Zendy

Júlia Gatti Ladeia Costa | Zendy; Ana Carolina Aguiar Vasconcelos Carneiro | Zendy; Alice Thomáz Tavares | Zendy; Gláucia Manzan Queiroz de Andrade | Zendy; Ricardo Wagner Almeida Vítor | Zendy; José Nelio Januário | Zendy; Daniel MenezesSouza | Zendy; Ricardo Toshio Fujiwara | Zendy

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Real-Time PCR as a Prognostic Tool for Human Congenital Toxoplasmosis

Author(s) -

Júlia Gatti Ladeia Costa,

Ana Carolina Aguiar Vasconcelos Carneiro,

Alice Thomáz Tavares,

Gláucia Manzan Queiroz de Andrade,

Ricardo Wagner Almeida Vítor,

José Nelio Januário,

Daniel MenezesSouza,

Ricardo Toshio Fujiwara

Publication year - 2013

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.00982-13

Subject(s) - toxoplasmosis , medicine , congenital toxoplasmosis , virology , biology , immunology , toxoplasma gondii , antibody

Real-time PCR (qPCR) was positive in 72/150 (48%) blood samples of newborns with congenital toxoplasmosis. Among infants with active retinochoroiditis, 68% had positive qPCR results, while positivity was 29% (P=0.009) in the absence of ocular involvement. Positive qPCR was associated with the presence of retinochoroidal lesions, with an odds ratio of 2.8.

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