Open AccessHospital-Based Evaluation of Two Rapid Human Immunodeficiency Virus Antibody Screening Tests
Author(s) -
Rajesh Kannangai,
Sandeep Ramalingam,
Pradeep Selvaraj,
Kannan Damodharan,
Gopalan Sridharan
Publication year - 2008
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00886-08
Subject(s) - virology , antibody , human immunodeficiency virus (hiv) , viral disease , sida , medicine , immunopathology , biology , immunology
Two rapid human immunodeficiency virus (HIV) screening assays, HIV TRI-DOT and HIV-SPOT were compared with standard enzyme-linked immunosorbent assays according to a testing algorithm. Sensitivities and specificities in the real-time evaluation were 99.5 and 99.9% for TRI-DOT and 98.2 and 99.7% for HIV-SPOT, respectively. These two tests are suitable for use where facilities and laboratory expertise are limited.
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