Extremes of Age Are Associated with Indeterminate QuantiFERON-TB Gold Assay Results | Zendy

Marc Tebruegge | Zendy; Hans de Graaf | Zendy; Priya Sukhtankar | Zendy; Paul Elkington | Zendy; Ben G. Marshall | Zendy; H.U. SCHUSTER | Zendy; Sanjay Patel | Zendy; Saul N. Faust | Zendy

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Extremes of Age Are Associated with Indeterminate QuantiFERON-TB Gold Assay Results

Author(s) -

Marc Tebruegge,

Hans de Graaf,

Priya Sukhtankar,

Paul Elkington,

Ben G. Marshall,

H.U. SCHUSTER,

Sanjay Patel,

Saul N. Faust

Publication year - 2014

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.00814-14

Subject(s) - indeterminate , quantiferon , gold standard (test) , medicine , tuberculosis , mycobacterium tuberculosis , pathology , mathematics , latent tuberculosis , pure mathematics

Results from 3,263 QuantiFERON-TB Gold in-tube (QFT-GIT) assays were analyzed to determine the impact of age on test performance. The proportion of indeterminate results was significantly higher in pediatric and elderly (9.1% and 7.4%, respectively) than in adult (2.6%; chi-square test, P < 0.0001) patients. A detailed analysis of indeterminate QFT-GIT assay results is presented.

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