Comparison of Three Adenovirus Quantitative PCR Assays with ATCC Reference Strains and Clinical Samples | Zendy

Kimberly Starr | Zendy; Alexander L. Greninger | Zendy; Negar Makhsous | Zendy; Keith R. Jerome | Zendy; Linda Cook | Zendy

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Comparison of Three Adenovirus Quantitative PCR Assays with ATCC Reference Strains and Clinical Samples

Author(s) -

Kimberly Starr,

Alexander L. Greninger,

Negar Makhsous,

Keith R. Jerome,

Linda Cook

Publication year - 2019

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.00735-19

Subject(s) - biology , virology , polymerase chain reaction , clinical microbiology , microbiology and biotechnology , genetics , gene

Adenoviruses (AdV) have been associated with a variety of human diseases and are recognized as causing significant morbidity and mortality in immunocompromised or transplant patients. Quantification of AdV DNA in plasma is notoriously difficult due to the genetic diversity of the 71 different serotypes identified to date. There is no World Health Organization standard available to harmonize quantitative data, so results between labs vary widely.

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