Comparative Analysis of Rabies Virus Reverse Transcription-PCR and Virus Isolation Using Samples from a Patient Infected with Rabies Virus | Zendy

Marcus Panning | Zendy; Sigrid Baumgarte | Zendy; Susanne Pfefferle | Zendy; Tanja Maier | Zendy; Andreas Martens | Zendy; Christian Drosten | Zendy

Open Access

Comparative Analysis of Rabies Virus Reverse Transcription-PCR and Virus Isolation Using Samples from a Patient Infected with Rabies Virus

Author(s) -

Marcus Panning,

Sigrid Baumgarte,

Susanne Pfefferle,

Tanja Maier,

Andreas Martens,

Christian Drosten

Publication year - 2010

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.00728-10

Subject(s) - rabies virus , virology , rabies , virus , virus isolation , biology , lyssavirus , reverse transcription polymerase chain reaction , mononegavirales , isolation (microbiology) , rhabdoviridae , viral disease , microbiology and biotechnology , paramyxoviridae , gene , messenger rna , genetics

Definite and rapid diagnosis of rabies is required for individual case management as well as for public health. For the first time, a direct comparison of virus isolation with quantitative real-time reverse transcription (RT)-PCR on human rabies samples was conducted. RT-PCR was found to be more sensitive than virus isolation.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research