Open AccessFrequency of Panton-Valentine Leukocidin-Producing Methicillin-Sensitive Staphylococcus Strains in Patients with Complicated Skin and Soft Tissue Infection in Bronx, New York
Author(s) -
Anna Kaltsas,
Alice Guh,
José R. Mediavilla,
Ankur Nandan Varshney,
Natalie Robiou,
Philip Gialanellia,
Michael Henry,
Michael H. Levi,
Bettina C. Fries
Publication year - 2011
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00704-11
Subject(s) - panton–valentine leukocidin , staphylococcus aureus , leukocidin , methicillin resistant staphylococcus aureus , microbiology and biotechnology , staphylococcal skin infections , medicine , enterotoxin , soft tissue , micrococcaceae , virology , biology , antibacterial agent , surgery , bacteria , antibiotics , gene , genetics , escherichia coli
lukF -PV was present in 36% of skin and soft tissue infection (SSTI)-derived methicillin-susceptibleStaphylococcus aureus (MSSA) strains and comprised six distinct clones, which contained fewer enterotoxin genes than strains withoutlukF -PV . Clinical presentations and outcomes oflukF -PV + methicillin-resistantS. aureus (MRSA) and MSSA SSTIs were comparable. In multivariable analysis, the presence oflukF -PV remained a significant predictor for incision and drainage among MSSA strains.