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Serodiagnosis of Mycobacterium avium Complex and Mycobacterium abscessus Complex Pulmonary Disease by Use of IgA Antibodies to Glycopeptidolipid Core Antigen
Author(s) -
ByeongHo Jeong,
SuYoung Kim,
Kyeongman Jeon,
SooYoun Lee,
Sung Jae Shin,
WonJung Koh
Publication year - 2013
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00702-13
Subject(s) - mycobacterium , antigen , immunoassay , mycobacterium abscessus , antibody , mycobacterium avium complex , mycobacterium tuberculosis , microbiology and biotechnology , pulmonary disease , monoclonal antibody , mycobacterium avium intracellulare infection , tuberculosis , virology , immunology , biology , medicine , pathology
An enzyme immunoassay kit that detects serum IgA antibody reacting to glycopeptidolipid core antigen derived from Mycobacterium avium complex (MAC) was not useful for differentiating MAC pulmonary disease (PD) from Mycobacterium abscessus complex PD (MAB-PD). However, this assay could be useful for differentiating MAC- and MAB-PD from pulmonary tuberculosis. (This study has been registered at ClinicalTrials.gov under registration no. NCT00970801.).

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