Depressed Gamma Interferon Responses and Treatment Outcomes in Tuberculosis Patients: a Prospective Cohort Study
Author(s) -
JiaYih Feng,
ShengWei Pan,
ShiangFen Huang,
Yingying Chen,
Yung-Yang Lin,
WeiJuin Su
Publication year - 2018
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00664-18
Subject(s) - tuberculosis , medicine , mycobacterium tuberculosis , immunosuppression , prospective cohort study , immunology , interferon gamma , tb treatment , pathogenesis , cohort , cohort study , directly observed therapy , cytokine , pathology
Immunosuppression induced byMycobacterium tuberculosis is important in the pathogenesis of active tuberculosis (TB). However, the impact of depressed TB-specific and non-TB-specific gamma interferon (IFN-γ) response on the treatment outcomes of TB patients remains uncertain.
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