Open AccessDetection of Inducible Clindamycin Resistance in Beta-Hemolytic Streptococci by Using the CLSI Broth Microdilution Test and Erythromycin-Clindamycin Combinations
Author(s) -
Jason E. Bowling,
Aaron Owens,
M. Leticia McElmeel,
Letitia C. Fulcher,
Mónica Herrera,
Brian L. Wickes,
James H. Jorgensen
Publication year - 2010
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00663-10
Subject(s) - broth microdilution , clindamycin , microbiology and biotechnology , erythromycin , streptococcaceae , antibacterial agent , biology , antibiotics , minimum inhibitory concentration
This study assessed an erythromycin-clindamycin (ERY-CC) broth test for inducible CC resistance in beta-hemolytic streptococci. One hundred one isolates of groups A, B, C, F, and G were tested by the CLSI broth microdilution method. Combinations of 1 and 0.25 μg/ml or 0.5 and 0.25 μg/ml of ERY and CC, respectively, detected all inducible isolates.