Analysis of Vancomycin Susceptibility Testing Results for Presumptive Categorization of Telavancin | Zendy

Rodrigo E. Mendes | Zendy; David J. Farrell | Zendy; Robert K. Flamm | Zendy; Hélio S. Sader | Zendy; Ronald N. Jones | Zendy

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Analysis of Vancomycin Susceptibility Testing Results for Presumptive Categorization of Telavancin

Author(s) -

Rodrigo E. Mendes,

David J. Farrell,

Robert K. Flamm,

Hélio S. Sader,

Ronald N. Jones

Publication year - 2015

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.00611-15

Subject(s) - vancomycin , teicoplanin , enterococcus faecalis , microbiology and biotechnology , staphylococcus aureus , biology , bacteria , genetics

Scattergrams between vancomycin and telavancin demonstrated susceptibility agreement rates of 99.96, 99.65, and 100.00% forStaphylococcus aureus ,Enterococcus faecalis , and streptococci, respectively. A single very major error was obtained againstE. faecalis , while vancomycin-intermediateS. aureus (VISA) and vancomycin-resistant and teicoplanin-susceptible (VanB phenotype)E. faecalis were responsible for major and minor errors. These results support the use of vancomycin to infer telavancin susceptibility among indicated pathogens, except VISA, which should be tested for telavancin susceptibility.

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