Vancomycin Heteroresistance in Bloodstream Isolates of Staphylococcus capitis | Zendy

Danaë D'mello | Zendy; Andrew J. Daley | Zendy; Muhammad Shihab Rahman | Zendy; Yue Qu | Zendy; Suzanne M. Garland | Zendy; Christopher Pearce | Zendy; Margaret Deighton | Zendy

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Vancomycin Heteroresistance in Bloodstream Isolates of Staphylococcus capitis

Author(s) -

Danaë D'mello,

Andrew J. Daley,

Muhammad Shihab Rahman,

Yue Qu,

Suzanne M. Garland,

Christopher Pearce,

Margaret Deighton

Publication year - 2008

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.00592-08

Subject(s) - vancomycin , etest , microbiology and biotechnology , staphylococcus aureus , micrococcaceae , biology , bacteremia , population , staphylococcus , antibacterial agent , medicine , antibiotics , bacteria , genetics , environmental health

Nine Staphylococcus capitis isolates from blood cultures of newborns were examined for resistance to vancomycin. MICs were within the susceptible range, but population profiling revealed a resistant subpopulation. Only isolates with the largest subpopulation were identified as heteroresistant to vancomycin by Etest. This finding may have therapeutic implications.

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