Open AccessDetection of Prosthetic Joint Infection by Use of PCR-Electrospray Ionization Mass Spectrometry Applied to Synovial Fluid
Author(s) -
Dante P. Melendez,
James R. Uhl,
Kerryl E. GreenwoodQuaintance,
Arlen D. Hanssen,
Rangarajan Sampath,
Robin Patel
Publication year - 2014
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00570-14
Subject(s) - synovial fluid , mass spectrometry , electrospray ionization , chromatography , electrospray , chemistry , medicine , microbiology and biotechnology , pathology , biology , osteoarthritis , alternative medicine
PCR coupled with electrospray ionization mass spectrometry applied to synovial fluid specimens had an 81% sensitivity and a 95% specificity for the diagnosis of prosthetic joint infection.
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