Direct Detection of Mycobacterium tuberculosis Complex in Clinical Samples by a Molecular Method Based on GenoQuick Technology | Zendy

Raquel Moure | Zendy; Miriam Torres | Zendy; R. Russell Martin | Zendy; Fernando Alcaide | Zendy

Open Access

Direct Detection of Mycobacterium tuberculosis Complex in Clinical Samples by a Molecular Method Based on GenoQuick Technology

Author(s) -

Raquel Moure,

Miriam Torres,

R. Russell Martin,

Fernando Alcaide

Publication year - 2012

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.00567-12

Subject(s) - mycobacterium tuberculosis complex , nontuberculous mycobacteria , tuberculosis , mycobacterium tuberculosis , mycobacterium , microbiology and biotechnology , biology , mycobacterium avium complex , virology , medicine , pathology

Several molecular systems for direct detection ofMycobacterium tuberculosis complex (MTBC) have recently been developed. The GenoQuick MTB assay (GQ-MTB) used in this study detected 82 of the 96 (85.4%) samples with MTBC, including 50 of 64 (78.1%) samples with negative acid-fast bacillus smears. Fifteen samples containing nontuberculous mycobacteria were also studied: 13 were GQ-MTB negative, one was positive, and one was indeterminate. GQ-MTB showed good effectiveness for the direct detection of MTBC from clinical samples.

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