Introduction to Measurement of Avidity of Anti-Coxiella burnetii IgG in Diagnosis of Q Fever | Zendy

Léa Luciani | Zendy; Coralie L’Ollivier | Zendy; Matthieu Million | Zendy; Bernard Amphoux | Zendy; Sophie Edouard | Zendy; Didier Raoult | Zendy

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Introduction to Measurement of Avidity of Anti-Coxiella burnetii IgG in Diagnosis of Q Fever

Author(s) -

Léa Luciani,

Coralie L’Ollivier,

Matthieu Million,

Bernard Amphoux,

Sophie Edouard,

Didier Raoult

Publication year - 2019

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.00539-19

Subject(s) - avidity , serology , coxiella burnetii , q fever , titer , immunology , antibody , virology , medicine , biology

Due to the atypical serological profile of some patients with primary Q fever infection who do not develop IgM againstCoxiella burnetii , we developed an avidity test to distinguish recent or past infections. We tested 39 serum samples by immunofluorescence with conventional assay and after urea treatment from 26 patients at different stages of the disease.

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