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Pseudomonas aeruginosa , a frequent pathogen in the intensive care unit (ICU), has the propensity to develop antibiotic resistance. In particular, carbapenem-nonsusceptible (NS)P. aeruginosa poses tremendous challenges, and new antibiotics will be needed to treat this phenotype. Here we determine carbapenem nonsusceptibility rates for contemporaryP. aeruginosa isolates from U.S. ICUs andin vitro activities of new β-lactam combination agents.

journal of clinical microbiology

Carbapenem-Nonsusceptible <i>Pseudomonas aeruginosa</i> Isolates from Intensive Care Units in the United States: a Potential Role for New β-Lactam Combination Agents

Carbapenem-Nonsusceptible Pseudomonas aeruginosa Isolates from Intensive Care Units in the United States: a Potential Role for New β-Lactam Combination Agents