Comparison of the Abbott m 2000 RealTi m e CT Assay and the Cepheid GeneXpert CT/NG Assay to the Roche Amplicor CT Assay for Detection of Chlamydia trachomatis in Ocular Samples from Tanzania | Zendy

Laura Dize | Zendy; Sheila K. West | Zendy; James A. Williams | Zendy; Barbara Van Der Pol | Zendy; Thomas C. Quinn | Zendy; Charlotte A. Gaydos | Zendy

Open Access

Comparison of the Abbott m 2000 RealTi m e CT Assay and the Cepheid GeneXpert CT/NG Assay to the Roche Amplicor CT Assay for Detection of Chlamydia trachomatis in Ocular Samples from Tanzania

Author(s) -

Laura Dize,

Sheila K. West,

James A. Williams,

Barbara Van Der Pol,

Thomas C. Quinn,

Charlotte A. Gaydos

Publication year - 2013

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.00519-13

Subject(s) - genexpert mtb/rif , chlamydia trachomatis , confidence interval , medicine , virology , chlamydia , chlamydiaceae , chlamydiales , biology , tuberculosis , immunology , pathology , mycobacterium tuberculosis

The GeneXpert CT/NG assay (GeneXpert) and the Abbott m2000 RealTime CT (m2000) assay were compared to Amplicor for detecting ocular Chlamydia trachomatis. Discordant specimens were tested by the Aptima CT assay. The m2000 assay sensitivity was 100% (95% confidence interval [CI], 90% to 100%), and specificity was 98.46% (95% CI, 95.2% to 99.2%); GeneXpert sensitivity was 100% (95% CI, 90% to 100%), and specificity was 100% (95% CI, 98.1% to 100%). The m2000 and GeneXpert assays appear to perform as well as the Amplicor assay.

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