Cross-Infection of Solid Organ Transplant Recipients by a Multidrug-Resistant Klebsiella pneumoniae Isolate Producing the OXA-48 Carbapenemase, Likely Derived from a Multiorgan Donor | Zendy

Tommaso Giani | Zendy; Viola Conte | Zendy; Salvatore Mandalà | Zendy; Marco Maria D’Andrea | Zendy; Francesco Luzzaro | Zendy; Pier Giulio Conaldi | Zendy; Paolo Grossi | Zendy; Gian María Rossolini | Zendy

Open Access

Cross-Infection of Solid Organ Transplant Recipients by a Multidrug-Resistant Klebsiella pneumoniae Isolate Producing the OXA-48 Carbapenemase, Likely Derived from a Multiorgan Donor

Author(s) -

Tommaso Giani,

Viola Conte,

Salvatore Mandalà,

Marco Maria D’Andrea,

Francesco Luzzaro,

Pier Giulio Conaldi,

Paolo Grossi,

Gian María Rossolini

Publication year - 2014

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.00511-14

Subject(s) - klebsiella pneumoniae , microbiology and biotechnology , multiple drug resistance , solid organ , organ transplantation , carriage , biology , klebsiella , medicine , transplantation , drug resistance , escherichia coli , pathology , gene , biochemistry

We describe two cases of bacteremic infections caused by a multidrug-resistant Klebsiella pneumoniae isolate producing the OXA-48 carbapenemase that occurred in two solid organ transplant (liver and kidney) recipients, which was apparently transmitted with the allografts. This finding underscores the risk of donor-derived infections by multidrug-resistant Gram-negative pathogens in solid organ transplant recipients and emphasizes the need for rapid screening of organ donors for carriage of similar pathogens.

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