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Scrub Typhus with Sepsis and Acute Respiratory Distress Syndrome
Author(s) -
Asok Kurup,
Aneesh Issac,
Jin Phang Loh,
Too Bou Lee,
Robert Lorenz Chua,
Pradeep Bist,
ChienChung Chao,
Michael Lewis,
Duane J. Gubler,
Wei Mei Ching,
Eng Eong Ooi,
Bindu Sukumaran
Publication year - 2013
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00463-13
Subject(s) - eschar , scrub typhus , pathognomonic , orientia tsutsugamushi , medicine , acute respiratory distress , doxycycline , respiratory distress , sepsis , septic shock , typhus , intensive care medicine , rickettsiosis , differential diagnosis , pediatrics , immunology , disease , pathology , virology , surgery , rickettsia , biology , antibiotics , microbiology and biotechnology , lung , virus
Scrub typhus is a major infectious threat in the Asia-Pacific region. We report an unusual case of scrub typhus in a patient in Singapore who presented with sepsis and acute respiratory distress syndrome but lacked the pathognomonic eschar. The patient recovered after appropriate diagnosis and doxycycline treatment. Rickettsial diseases should be included in the differential diagnosis of febrile illnesses in regions where the diseases are endemic, and absence of eschar should not be the criterion used to rule out scrub typhus.

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